Aging is a complex process determined by both genetic and environmental factors. By manipulating these aging-related factors, researchers have been able to extend lifespan and healthspan in lab animals. This course is mainly focused on the current and emerging interventions to promote human lifespan and healthspan. In this course, learners will learn both general knowledge and mechanistic insights into these anti-aging interventions.
The goals of the course are to: (1) understand the concept of lifespan modulation by both intrinsic and extrinsic factors; (2) appreciate important environmental factors involved in human aging; and (3) promote critical thinking of clinical implications of environmental interventions for age-associated conditions
|Module 1||Overview of aging-related environmental factors|
|Module 2||Experimental models for laboratory aging research|
|Module 3||Dietary intervention for anti-aging: dietary restriction|
|Module 4||Dietary intervention for anti-aging: gut microbiome|
|Module 5||Exercise and Aging|
|Module 6||Social interaction for anti-aging|
|Module 7||Anti-aging Compound and their Mechanisms of Actions|
|Module 8||Hypothermia therapy and anti-aging|
|Module 9||Environmental enrichment and anti-aging|
|Module 10||“Young Blood” Transfusion and anti-aging|
|Module 11||Clearing senescent cells for anti-aging|
|Module 12||Anti-aging gene therapy: advances and challenges|
|Module 13||Stem cell and anti-aging|
|Module 14||Modern biotechnology for potential anti-aging intervention|
|Module 15||Final Project|
- Topic articles will be placed on the course website. The information in these articles is coordinated with online lecture materials and serves as the required text for the course.
- Weekly discussion questions will stimulate critical thinking about issues relevant for that week’s topic.
- An on-line discussion will be available every week to address questions related to the lectures or other learning material.
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